Alvimopan Addition to a Standard Perioperative Recovery Pathway

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Alvimopan Addition to a Standard Perioperative Recovery Pathway

BACKGROUND AND OBJECTIVES Alvimopan, a peripherally acting mu-opioid receptor antagonist, decreased time to gastrointestinal recovery and hospital length of stay in open bowel resection patients in Phase 3 trials. However, the benefit in laparoscopic colectomy patients remains unclear. METHODS A retrospective case series review was performed to study addition of alvimopan to a well-establish...

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Delayed gastrointestinal recovery after abdominal operation – role of alvimopan

Postoperative Ileus (POI), which occurs after surgical manipulation of the bowel during abdominal operations, is associated with prolonged hospital stay, increasing medical costs, and delayed advancement of enteral diet, which contributes to a significant economic burden on the healthcare system. The use of accelerated care pathways has shown to positively impact gut function, but inevitable po...

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Alvimopan in an Enhanced Recovery Program Following Radical Cystectomy

Background: Radical cystectomy (RC) carries a high complication rate, including post-operative ileus. Alvimopan is an FDA approved peripherally acting μ-opioid receptor antagonist that has shown favorable results for improved recovery of gastro-intestinal function resulting in decreased hospital length of stay. Many enhanced recovery pathways (ERP) have been published demonstrating improved out...

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Alvimopan and enhanced recovery pathways in colorectal surgery

Postoperative ileus negatively impacts patient outcomes and healthcare utilization, increasing both postoperative length of stay and health care costs. In efforts to optimize perioperative care, efforts have been placed into developing tools to minimize postoperative ileus. Alvimopan (Entereg®) was developed to meet this need. Alvimopan has permitted accelerated return of bowel function after a...

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Standard Addition Connected to Selective Zone Discovering for Quantification in the Unknown Mixtures

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ژورنال

عنوان ژورنال: JSLS : Journal of the Society of Laparoendoscopic Surgeons

سال: 2011

ISSN: 1086-8089,1938-3797

DOI: 10.4293/108680811x13176785204076